The Senegal superstar netted once as Liverpool's fearsome threesome of strikers hit all the Reds' five goals in Tuesday's exhilarating win over Roma.
But a question mark must hang over Mane's fitness after the Mail reported he spent 30 minutes at Liverpool's Spire Hospital today.
The Reds host Stoke in the Premier League this Saturday before travelling to the Italian capital on Wednesday with a 5-2 lead for their Champions League semi-final return leg.
Mane hit the third Liverpool goal against Roma at Anfield and played the whole 90 minutes, seemingly untroubled.
But Roma would surely love to see the 26-year-old miss the second leg.
That is because Mane, Roberto Firmino and especially Mo Salah form arguably the best counter-attacking frontline in the world.
And Roma wil be worried about Liverpool bagging the away goal that would make it extra difficult for the Serie A giants to go through.
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In-form England midfielder Alex Oxlade-Chamberlain is already sure to miss the clash in Rome as a knee ligament suffered on Tuesday ruled him out for the rest of the domestic season – and the World Cup.
Reds boss Jurgen Klopp will certainly take no chances with his line-up this weekend against second-bottom Stoke.
The Champions League is now Liverpool's overwhelming priority.
Klopp said: “The biggest problem we have is that we lost Oxlade-Chamberlain who played brilliant for as long as he was on the pitch.
"Thank God [Georginio] Wijnaldum played fantastic as well, but that’s a serious injury and with our squad situation at the moment it’s of course not really cool.
“And we all know the best thing is that if you want to go to semi-final, finals and win important games in the league, you need a full squad.
“So we have to find solutions and be creative and that’s what we will try to be.”
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