USA TODAY Sports’ Week 6 NFL picks: Can Patriots, Tom Brady take down unbeaten Chiefs?

Week 6 of the NFL season comes with some tantalizing games, perhaps none more intriguing than the undefeated Chiefs visit to New England, site of Kansas City's massive upset of the Patriots to kick off the 2017 season. Of course, this time, Patrick Mahomes is under center for K.C. and will take aim at what's been an up-and-down Pats defense.

Elsewhere, Pittsburgh will try to knock off the first-place Bengals in Cincinnati — and Paul Brown Stadium has been an alternate home field for the Steelers in recent years.

Elsewhere, the Browns are seeking consecutive wins for the first time in nearly four years, while the Raiders and Seahawks kick off this year's International Series with London's Wembley Stadium hosting the Marshawn Lynch Bowl.

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