The pair became close when they played frenemies Peggy Mitchell and Pat Butcher in the hit BBC soap.
In May, The Sun revealed how Babs had been battling Alzheimer's for four years after being diagnosed in 2014.
Today Pam has revealed she hasn’t been allowed to visit her pal because Dame Barbara's condition has got worse in recent weeks.
The 76-year-old actress told the Daily Star Sunday: “I’m sad I haven’t been able to visit Barbara due to her illness.
“I have been in constant touch with Scott, Barbara’s husband, but I couldn’t speak to Barbara directly in case it confused her.
“Any plans to see her have also had to be put on hold because she is poorly.”
Just last month fellow EastEnders star Rita Simmons revealed her devastation of Babs' Alzheimer's battle.
The actress – who played Roxy Mitchell in the BBC soap until she was axed last year – told how the legendary Dame had a "dip" lately which is heartbreaking for her husband Scott and all her family and friends.
She told the Daily Star Sunday: “From what her husband Scott Mitchell said to me, she has had a real dip lately.
“What I have seen is more confusion, which is really devastating to watch because she always had her marbles together and was always the life and soul of the room.
“It is an incredibly sad thought that my Aunty Peggy, which is what I’ve always called Barbara, isn't herself."
Rita added: "From what Scott says there are some dark days but they still have good days, too.
“Scott is doing an amazing job. I don’t know what she would do without Scott."
It came just days after Dame Barbara's on-screen son Ross Kemp had an emotional meeting with her as she bravely battles the cruel disease.
The 53-year-old actor shared a sweet snap of him with his on-screen mother after popping round to visit.
But having spent time with Barbara – who played his mum Peggy Mitchell in EastEnders – Ross revealed she was in great spirits.
Appearing on Good Morning Britain, the actor – who played Grant Mitchell – said: "Put it this way, I went round for a cup of tea and I was there for three-and-a-half hours.
"I think what she's done is very brave, she has a great husband in Scott [Mitchell], he's been very supportive."
As hosts Ben Shephard and Susanna Reid asked if she was doing OK, Ross continued: "Honestly, I had five cups of tea, three shortbread biscuits – which is not good for my diet – and I laughed a lot.
"She's got that great ability, when you walk through the door, she's 'on'.
"It was like seeing my second mum."
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